Under the leadership of Dr. Graham Richards, Director of NFCR Center for Computational Drug Discovery (NFCR-CCDD) at the University of Oxford, the Screensaver-Lifesaver Program has made a significant impact in discovering novel anticancer drugs. The virtual supercomputer has generated thousands of lead molecules and promising anticancer drug candidates from screening 3.5 billion chemical compounds against 14 major cancer related protein targets. Many lead compounds are being synthesized and tested for their anticancer effects, investigated and optimized by a cross-disciplinary team at the NFCR-CCDD, and utilized by scientists of other institutes for new anticancer drug development.